MRE 3008F20

Names

[ Name ]:
MRE 3008F20

Biological Activity

[Description]:

MRE3008F20 is a highly potent and selective antagonistic of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[Target]

IC50 : 5 nM (AA3R, resting T lymphocytes)[1]

[References]

[1]. Gessi S, et al. Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation. Mol Pharmacol. 2004 Mar;65(3):711-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₀N₈O₃

[ Molecular Weight ]:
432.44

[ Exact Mass ]:
432.16600

[ PSA ]:
127.63000

[ LogP ]:
3.29150

Related Compounds

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