Antiparasitic agent-2

Names

[ CAS No. ]:
2494277-80-2

[ Name ]:
Antiparasitic agent-2

Biological Activity

[Description]:

Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM)[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 7.28 μM (L. infantum), 2.30 μM (T. cruzi)[1]


[References]

[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H17N3O3

[ Molecular Weight ]:
347.37

Related Compounds