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L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride

Names

[ CAS No. ]:
2483829-89-4

[ Name ]:
L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride

Biological Activity

[Description]:

L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
13C4H9ClN215N2O2

[ Molecular Weight ]:
186.55


Related Compounds

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