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Pipendoxifene hydrochloride

Names

[ CAS No. ]:
245124-69-0

[ Name ]:
Pipendoxifene hydrochloride

[Synonym ]:
2-(4-Hydroxyphenyl)-3-methyl-1-{4-[2-(1-piperidinyl)ethoxy]benzyl}-1H-indol-5-ol hydrochloride (1:1)
1H-Indol-5-ol, 2-(4-hydroxyphenyl)-3-methyl-1-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-, hydrochloride (1:1)
Pipendoxifene (hydrochloride)

Biological Activity

[Description]:

Pipendoxifene hydrochloride is a selective estrogen receptor modulators (SERMs).

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR
Research Areas >> Cancer

[Target]

Estrogen receptor[1]


[In Vitro]

Pipendoxifene is a new 2-phenyl indole selective estrogen receptor modulators (SERM) that exhibits an excellent preclinical pharmacological profile and is selected for further development as a treatment for metastatic breast cancer[1].

[References]

[1]. Shelly W, et al. Selective estrogen receptor modulators: an update on recent clinical findings. Obstet Gynecol Surv. 2008 Mar;63(3):163-81.


[Related Small Molecules]

Elacestrant dihydrochloride | AZD9496 | Kaempferol | XCT 790 | Estrone | GDC-0810 | (20S)-Protopanaxatriol | 27-Hydroxycholesterol | Diethylstilbestrol | PHTPP | 2,3-bis(4-hydroxyphenyl)propionitrile | 4',7-Isoflavandiol | cholesterol | Chrysin | Endoxifen (Z-isomer hydrochloride)

Chemical & Physical Properties

[ Molecular Formula ]:
C29H33ClN2O3

[ Molecular Weight ]:
493.037

[ Exact Mass ]:
492.217957

[ Storage condition ]:
2-8℃

Related Compounds

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