Exatecan-amide-cyclopropanol

Names

[ CAS No. ]:
2414254-34-3

[ Name ]:
Exatecan-amide-cyclopropanol

Biological Activity

[Description]:

Exatecan-amide-cyclopropanol (compound 1) is a anticancer agent. Exatecan-amide-cyclopropanol shows anti-proliferation activity against SK-BR-3 and U87 cells, with IC50 values of 0.12 and 0.23 nM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Xu Jianyan, et al. Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof. WO2020063676A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H26FN3O6

[ Molecular Weight ]:
519.52


Related Compounds