Fenmetozole hydrochloride

Names

[ Name ]:
Fenmetozole hydrochloride

[Synonym ]:
2-((3,4-Dichlorophenoxy)methyl)-2-imidazoline hydrochloride
1H-Imidazole,2-((3,4-dichlorophenoxy)methyl)-4,5-dihydro-,monohydrochloride
Fenmetozole HCl
Fenmetozole hydrochloride
DH 524 (pharmaceutical)
Fenmetozole hydrochloride (USAN)
DH-524
2-IMIDAZOLINE,2-((3,4-DICHLOROPHENOXY)METHYL)-,MONOHYDROCHLORIDE

Biological Activity

[Description]:

Fenmetozole hydrochloride is an antagonist of ethanol, and also antagonizes α2-adrenergic receptor, which has antidepressant effect[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Neurological Disease

[References]

[1]. Stillings MR, et al. Effect of methoxy substitution on the adrenergic activity of three structurally related alpha 2-adrenoreceptor antagonists. J Med Chem. 1986 Sep;29(9):1780-3.

Chemical & Physical Properties

[ Density]:
1.43g/cm3

[ Boiling Point ]:
430ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₁Cl₃N₂O

[ Molecular Weight ]:
281.57

[ Flash Point ]:
213.8ºC

[ Exact Mass ]:
279.99400

[ PSA ]:
33.62000

[ LogP ]:
2.94030

Related Compounds

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