5-Dehydroepisterol

Names

[ Name ]:
5-Dehydroepisterol

[Synonym ]:
5-dehydroepisterol
Campesta-7,24(28)-dien-3beta-ol
ergosta-5,7,24(28)-trien-3beta-ol
24-Methylcholesta-5,7,24(28)-trienol
ergosta-5,7,24(28)-trien-3|A-ol
campesta-7,24(28)-dien-3|A-ol

Biological Activity

[Description]:

5-Dehydroepisterol is an episterol derivative and an intermediate in steroid biosynthesis. 5-Dehydroepisterol can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase. 5-Dehydroepisterol has anti-fungal activities[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[Target]

IC50: Intermediate in steroid biosynthesis[1]

[References]

[1]. 5-Dehydroepisterol. From Wikipedia

[2]. Rodrigues JC, et al. Ultrastructural and biochemical alterations induced by 22,26-azasterol, a delta(24(25))-sterol methyltransferase inhibitor, on promastigote and amastigote forms of Leishmania amazonensis.Antimicrob Agents Chemother. 2002 Feb;46(2):487-99.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₄₄O

[ Molecular Weight ]:
396.64800

[ Exact Mass ]:
396.33900

[ PSA ]:
20.23000

[ LogP ]:
7.47490

Related Compounds

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