alpha-D-glucose-d7

Names

[ Name ]:
alpha-D-glucose-d7

[Synonym ]:
MFCD00144081
D-Glucose-1,2,3,4,5,6,6-d7
(3R,4S,5S,6S)-2,3,4,5,6-pentadeuterio-6-[dideuterio(hydroxy)methyl]oxane-2,3,4,5-tetrol

Biological Activity

[Description]:

alpha-D-glucose-d7 is the deuterium labeled alpha-D-glucose[1]. alpha-D-glucose is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.799g/cm3

[ Boiling Point ]:
410.8ºC at 760 mmHg

[ Melting Point ]:
150-152ºC(lit.)

[ Molecular Formula ]:
C₆H₅D₇O₆

[ Molecular Weight ]:
187.19900

[ Flash Point ]:
202.2ºC

[ Exact Mass ]:
187.10700

[ PSA ]:
110.38000

[ Vapour Pressure ]:
1.83E-08mmHg at 25°C

[ Index of Refraction ]:
1.635

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport