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AHR antagonist 2

Names

[ CAS No. ]:
2338747-54-7

[ Name ]:
AHR antagonist 2

Biological Activity

[Description]:

AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1, with IC50s of 0.885 and 2.03 nM for human and mouse AhR[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> Aryl Hydrocarbon Receptor

[References]

[1]. Julien LEFRANC, et al. 2-hetarylpyrimidine-4-carboxamides as aryl hydrocarbon receptor anatgonists. WO2019101641A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H17F3N4O3

[ Molecular Weight ]:
418.37

Related Compounds