5,7-Diacetoxy-8-methoxyflavone

Names

[ Name ]:
5,7-Diacetoxy-8-methoxyflavone

[Synonym ]:
wogonin diacetate
5,7-Diacetoxy-8-methoxyflavone
5,7-Diacetoxy-8-methoxy-2-phenyl-chromen-4-on
4H-1-Benzopyran-4-one, 5,7-bis(acetyloxy)-8-methoxy-2-phenyl-
8-Methoxy-4-oxo-2-phenyl-4H-chromene-5,7-diyl diacetate
W1610
5,7-diacetoxy-8-methoxy-2-phenyl-chromen-4-one

Biological Activity

[Description]:

5,7-Diacetoxy-8-methoxyflavone is a natural product that could come from scutellaria genus plants. 5,7-Diacetoxy-8-methoxyflavone has inhibitory activity for cAMP phosphodiesterase[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

Research Areas >> Others

[References]

[1]. Nikaido T, et, al. Inhibition of adenosine 3',5'-cyclic monophosphate phosphodiesterase by flavonoids. II. Chem Pharm Bull (Tokyo). 1988 Feb;36(2):654-61.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
540.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₆O₇

[ Molecular Weight ]:
368.337

[ Flash Point ]:
238.3±30.2 °C

[ Exact Mass ]:
368.089600

[ PSA ]:
92.04000

[ LogP ]:
1.71

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.587

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2915390090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915390090

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%