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laccaic acid c

Names

[ CAS No. ]:
23241-56-7

[ Name ]:
laccaic acid c

[Synonym ]:
2-[5-(2-Carboxy-2-amino-ethyl)-2-hydroxy-phenyl]-7.8-dicarboxy-1.3.4.6-tetrahydroxy-anthrachinon
Laccainsaeure C
7-[5-(2-Amino-2-carboxyethyl)-2-hydroxyphenyl]-9,10-dihydro-3,5,6,8-tetrahydroxy-9,10-dioxo-1,2-anthracenedicarboxylic acid
7-[2-Hydroxy-5-(2-carboxy-2-aminoethyl)phenyl]-3,5,6,8-tetrahydroxy-9,10-dioxo-9,10-dihydro-1,2-anthracenedicarboxylic acid

Biological Activity

[Description]:

Laccaic acid C is an potent inhibitor of RNase H with an IC50 of 8.1 μM. Laccaic acid C also inhibits viral proliferation in cell [1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[References]

[1]. Ito Y, et al. Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase. J Nat Prod. 2023 Oct 24.  

Chemical & Physical Properties

[ Density]:
1.863g/cm3

[ Boiling Point ]:
970.965ºC at 760 mmHg

[ Molecular Formula ]:
C25H17NO13

[ Molecular Weight ]:
539.40100

[ Flash Point ]:
541.02ºC

[ Exact Mass ]:
539.07000

[ PSA ]:
273.21000

[ LogP ]:
1.70810

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.818

Preparation


Related Compounds