Monoethyl phthalate

Names

[ Name ]:
Monoethyl phthalate

[Synonym ]:
Phthalic acid,monoethyl ester
1,2-Benzenecarboxylic acid,monoethyl ester
o-phthalic acid monoethyl ester
Monoethyl phthalate
2-ethoxycarbonylbenzoic acid
2-(Ethoxycarbonyl)benzoic acid
Ethyl 2-Carboxybenzoate
1,2-Benzenedicarboxylic acid, monoethyl ester
1,2-Benzenedicarboxylic acid,monoethyl ester
1,2-Benzenedicarboxylic acid,monomethyl ester
monoethyl 1,2-benzenedicarboxylate

Biological Activity

[Description]:

Monoethyl phthalate is a phthalate metabolite, acts as a urinary biomarker of phthalates exposure indicating the risks of thyroid cancer and benign nodule[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Chong Liu, et al. Urinary biomarkers of phthalates exposure and risks of thyroid cancer and benign nodule. J Hazard Mater. 2020 Feb 5;383:121189.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
339.6±25.0 °C at 760 mmHg

[ Melting Point ]:
46-48ºC

[ Molecular Formula ]:
C₁₀H₁₀O₄

[ Molecular Weight ]:
194.184

[ Flash Point ]:
135.3±16.7 °C

[ Exact Mass ]:
194.057907

[ PSA ]:
63.60000

[ LogP ]:
1.66

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.547

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TI2495000

CHEMICAL NAME :: Phthalic acid, monoethyl ester

CAS REGISTRY NUMBER :: 2306-33-4

BEILSTEIN REFERENCE NO. :: 1956404

LAST UPDATED :: 199710

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H10-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHDDAT Comptes Rendus des Seances de l'Academie des Sciences, Serie D: Sciences Naturelles. (Paris, France) V.262-291, 1966-80. For publisher information, see CRASEV. Volume(issue)/page/year: 273,2165,1971

Safety Information

[ HS Code ]:
2918990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%