C18 CERAMIDE

Names

[ Name ]:
C18 CERAMIDE

[Synonym ]:
STEAROYL CERAMIDE
ceramide c18
N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)stearamide
N-Stearoyl-D-erythro-sphingosine
N-stearoylsphingosine
Cer(d18:1/18:0)
N-STEAROYLSPHINGANINE
C18 DIHYDROCERAMIDE
N-(octadecanoyl)-sphing-4-enine
N-18:0 SPHINGANINE
C18-D-ERYTHRO-CERAMIDE
N-stearoyl-D-erythro-sphingosine
N-Stearoyl-D-sphingosine
18:0 CERAMIDE
N-((2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl)stearamide
(2S,3R,4E)-2-(N-stearoylamino)-4-octadecene-1,3-diol
N-STEAROYL CERAMIDE

Biological Activity

[Description]:

C18-Ceramide can promote exocytosis of glutamate from damaged neurons. C18-Ceramide promotes cell death in glioma cells. Ceramides is involved in diverse cellular functions, such as differentiation, cell cycle progression, cell-cell adhesion, senescence, and apoptosis[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Tang N, et al. Differential effects of ceramide species on exocytosis in rat PC12 cells. Exp Brain Res. 2007 Nov;183(2):241-7.

[2]. Wang Z, et al. Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma. Oncotarget. 2017 Oct 23;8(61):104022-104036.

Chemical & Physical Properties

[ Density]:
0.915g/cm3

[ Boiling Point ]:
694.5ºC at 760 mmHg

[ Melting Point ]:
99 - 101ºC

[ Molecular Formula ]:
C₃₆H₇₁NO₃

[ Molecular Weight ]:
565.95400

[ Flash Point ]:
373.8ºC

[ Exact Mass ]:
565.54300

[ PSA ]:
69.56000

[ LogP ]:
10.73410

[ Vapour Pressure ]:
2.59E-22mmHg at 25°C

[ Index of Refraction ]:
1.479

[ Storage condition ]:
−20°C

[ Stability ]:
Stable, but may be heat sensitive - store below 4 C. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S24/25

[ HS Code ]:
29225000

Related Compounds

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