Dihydrofuran-3(2H)-one

Names

[ Name ]:
Dihydrofuran-3(2H)-one

[Synonym ]:
tetrahydrofuran-4-one
g-Butyrolactone
Dihydrofuran-3(2H)-one
gama-Butyrolactone
3-Oxo-1,4-epoxybutane
Dihydro-3(2H)-furanone
tetrahydrofuran-3-one
butyrolactone
Dihydrofuran-3-one
2(3H)-Furanone, dihydro-
2,3,4,5-Tetrahydro-2-furanone
3-ketotetrahydrofuran
tetrahydrofuran-2-one
3(2H)-Furanone, dihydro-
Dihydrofuran-2(3H)-one
1-Oxacyclopentan-2-one
3-Oxotetrahydrofuran
2-OXOTETRAHYDROFURAN
Dihydro-2(3H)-furanone
g-Hydroxybutyric Acid Lactone
3(2H)-Furanone, dihydro
4,5-Dihydro-2(3H)-furanone
γ-Butyrolactone
1-Oxacyclopentane-2-one
Tetrahydrofuran-3-yloxy
γ-Hydroxybutyric acid lactone
Dihydrofuran-3(2H)-on

Biological Activity

[Description]:

Dihydrofuran-3(2H)-one (3-Oxotetrahydrofuran) is used for synthesizing cyclic ketone inhibitors that inhibits the serine protease plasmin[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Xue F, et al. Structure-activity studies of cyclic ketone inhibitors of the serine protease plasmin: design, synthesis, and biological activity. Bioorg Med Chem. 2006 Dec 15;14(24):8467-87.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
151.1±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₆O₂

[ Molecular Weight ]:
86.089

[ Flash Point ]:
56.3±16.2 °C

[ Exact Mass ]:
86.036781

[ PSA ]:
26.30000

[ LogP ]:
-1.14

[ Vapour Pressure ]:
3.7±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.442

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S23-S26-S36/37/39

[ RIDADR ]:
UN 1993

[ HS Code ]:
2932190090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%