2'-Deoxy-N4-methylcytidine

Names

[ Name ]:
2'-Deoxy-N4-methylcytidine

[Synonym ]:
N(3)-Methyl-2'-deoxycytidine
2'-Deoxy-N(3)-methylcytidine
N4-methyl-2'-deoxycytidine
m3dC
2'-deoxy-N4-methyl-cytidine
Cytidine,2'-deoxy-N-methyl
2'-deoxy-4-N-methylcytidine
N-methyl-2'-deoxycytidine
2'-Deoxy-N4-methylcytidine

Biological Activity

[Description]:

2’-Deoxy-N4-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.56g/cm3

[ Boiling Point ]:
460.5ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₅N₃O₄

[ Molecular Weight ]:
241.24

[ Flash Point ]:
232.3ºC

[ Exact Mass ]:
241.10600

[ PSA ]:
100.10000

[ Vapour Pressure ]:
2.04E-10mmHg at 25°C

[ Index of Refraction ]:
1.665

[ Storage condition ]:
2-8℃

2'-Deoxy-N4-methylcytidine

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Related Compounds