6-CYCLOHEXYLHEXYL-BETA-D-MALTOSIDE

Names

[ Name ]:
6-CYCLOHEXYLHEXYL-BETA-D-MALTOSIDE

[Synonym ]:
Cymal-6
MA4
4fcf

Biological Activity

[Description]:

Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent TEM-1 beta-lactamase inhibitor with an Ki value of 40.05 µM. Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) can be used as glycosidic surfactant[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Ki: 40.05 µM (TEM-1 beta-lactamase)[1]

[References]

[1]. Avci FG, et al. Targeting a hidden site on class A beta-lactamases. J Mol Graph Model. 2018 Sep;84:125-133.

[2]. Ju M, et al. Enantioseparations by capillary electrophoresis using chiral glycosidic surfactants. II. Comparisonof chiral cyclohexyl-alkyl-β-D-maltoside surfactant. Journal of Liquid Chromatography & Related Technologies. 2000, 23(1):35-45.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₄₄O₁₁

[ Molecular Weight ]:
508.60000

[ Exact Mass ]:
508.28800

[ PSA ]:
178.53000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Crystallization of membrane proteins.

Curr. Opin. Struct. Biol. 7 , 697, (1997)

Five new membrane protein structures have been determined since 1995 using X-ray crystallography: bacterial light-harvesting complex; bacterial and mitochondrial cytochrome c oxidases; mitochondrial b...