Isoallolithocholic acid

Names

[ Name ]:
Isoallolithocholic acid

[Synonym ]:
lithocholic acid
Isoallolithocholate
3b-Hydroxy-5a-cholanate
Isoallolithocholic acid
3b-Hydroxy-5a-cholanoate
Alloisolithocholic acid
3b-hydroxy-5a-cholan-24-oic acid
Isolithocholic acid

Biological Activity

[Description]:

Alloisolithocholic acid (AILCA) activates large-conductance calcium-activated potassium (BK) channels with an EC50 value of 44.21 μM in Xenopus oocytes[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. Bukiya AN, et al. Structural determinants of monohydroxylated bile acids to activate beta 1 subunit-containing BK channels. J Lipid Res. 2008 Nov;49(11):2441-51.

Chemical & Physical Properties

[ Density]:
1.073g/cm3

[ Boiling Point ]:
511ºC at 760mmHg

[ Molecular Formula ]:
C₂₄H₄₀O₃

[ Molecular Weight ]:
376.57300

[ Flash Point ]:
276.9ºC

[ Exact Mass ]:
376.29800

[ PSA ]:
57.53000

[ LogP ]:
5.50710

[ Vapour Pressure ]:
1.4E-12mmHg at 25°C

[ Index of Refraction ]:
1.528

Isoallolithocholic acid

Names

Biological Activity

Chemical & Physical Properties

Related Compounds