HS-(CH2)3CO-L-Ala-D-Ala-L-Ala-NH-CH2-S-(CH2)5-CO-DM

Names

[ Name ]:
HS-(CH2)3CO-L-Ala-D-Ala-L-Ala-NH-CH2-S-(CH2)5-CO-DM

Biological Activity

[Description]:

HS-(CH2)3CO-L-Ala-D-Ala-L-Ala-NH-CH2-S-(CH2)5-CO-DM is a drug-linker (peptide-cleavable) conjugate for ADC. DM indicates the maytansinoid moiety[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Maytansinoids

[References]

[1]. Costoplus JA, et al. Peptide-Cleavable Self-immolative Maytansinoid Antibody-Drug Conjugates Designed To Provide Improved Bystander Killing. ACS Med Chem Lett. 2019;10(10):1393-1399. Published 2019 Sep 27.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₂H₇₈ClN₇O₁₄S₂

[ Molecular Weight ]:
1124.80

Related Compounds

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