IACS-8779 disodium

Names

[ Name ]:
IACS-8779 disodium

Biological Activity

[Description]:

IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. IACS-8779 disodium shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Immunology/Inflammation >> STING

[References]

[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₃N₉Na₂O₁₀P₂S₂

[ Molecular Weight ]:
733.52

Related Compounds

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