4-phenylbutan-2-amine

Names

[ Name ]:
4-phenylbutan-2-amine

[Synonym ]:
DL-1-methyl-3-phenyl-n-propylamine
α-Methyl phenethylamine
1-Methyl-3-phenylpropylamine
Benzenepropanamine, α-methyl-
1-phenyl-3-aminobutane
4-phenylbutan-2-amine
3-Amino-1-phenylbutane
EINECS 244-942-2
(RS)-1-methyl-3-phenylpropylamine
(+/-)-1-methyl-3-phenylpropylamine
4-Phenyl-2-aminobutane
4-Phenyl-2-butanamine
UNII:326655W66Z
α-Methylbenzenepropanamine
MFCD00056185
4-Phenyl-2-butylamine
2-Amino-4-phenylbutane

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
221.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-50ºC

[ Molecular Formula ]:
C₁₀H₁₅N

[ Molecular Weight ]:
149.233

[ Flash Point ]:
97.8±0.0 °C

[ Exact Mass ]:
149.120453

[ PSA ]:
26.02000

[ LogP ]:
2.18

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.522

[ Storage condition ]:
−20°C

[ Water Solubility ]:
8.5 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UI3920000

CHEMICAL NAME :: Propylamine, alpha-methyl-gamma-phenyl-

CAS REGISTRY NUMBER :: 22374-89-6

BEILSTEIN REFERENCE NO. :: 2413110

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H15-N

MOLECULAR WEIGHT :: 149.26

WISWESSER LINE NOTATION :: ZY1&2R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 195,647,1940

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 195,647,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 195,647,1940

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C: Corrosive;Xi: Irritant;T: Toxic;F: Flammable;

[ Risk Phrases ]:
R22;R34

[ Safety Phrases ]:
26-36/37/39-45-28A-36/37

[ RIDADR ]:
UN 2735 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
UI3920000

[ Packaging Group ]:
III

[ HS Code ]:
29214980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Preparation

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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