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CPA inhibitor

Names

[ CAS No. ]:
223532-02-3

[ Name ]:
CPA inhibitor

[Synonym ]:
CS-0335
CPA inhibitor

Biological Activity

[Description]:

CPA inhibitor is a potent inhibitor for carboxypeptidase A (CPA).

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Carboxypeptidase

Research Areas >> Metabolic Disease

[References]

[1]. Kumar P, et al. Meropenem inhibits D,D-carboxypeptidase activity in Mycobacterium tuberculosis.Mol Microbiol. 2012 Aug 21.

[2]. Zhang H, et al. Molecular dynamics and free energy studies on the carboxypeptidases complexed with peptide/small molecular inhibitor: mechanism for drug resistance.Insect Biochem Mol Biol. 2012 Aug;42(8):583-95. Epub 2012 Apr 23.

[3]. Kim, Dong H.; Jin, Yonghao.First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-? -phenylalanines. Bioorganic & Medicinal Chemistry Letters (1999), 9(5), 691-696.

[Related Small Molecules]

2-(Phosphonomethyl)pentanedioic acid | Carboxypeptidase G2 (CPG2) Inhibitor

Chemical & Physical Properties

[ Density]:
1.274

[ Molecular Formula ]:
C₁₈H₁₉NO₄

[ Molecular Weight ]:
313.34800

[ Exact Mass ]:
313.13100

[ PSA ]:
77.84000

[ LogP ]:
2.39040

[ Storage condition ]:
2-8℃

Related Compounds