ONO 4817

Names

[ Name ]:
ONO 4817

[Synonym ]:
ono 4817

Biological Activity

[Description]:

ONO-4817 is a potent inhibitor of matrix metalloproteinase (MMP). Inhibition of matrix metalloproteinases (MMPs) is expected to suppress atherosclerotic neointimal proliferation and thus limits atheromatous plaque progression. ONO-4817 suppresses the development of aortic intimal hyperplasia in experimental hyperlipidemic rabbit[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[References]

[1]. Okamoto Y, et al. A matrix metalloproteinase inhibitor, ONO-4817, suppresses the development of aortic intimal hyperplasia in experimental hyperlipidemic rabbit. Int Heart J. 2007;48(3):369-378.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₈N₂O₆

[ Molecular Weight ]:
416.46800

[ Exact Mass ]:
416.19500

[ PSA ]:
106.12000

[ LogP ]:
3.90130

Related Compounds

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