Pomalidomide-C7-COOH

Names

[ Name ]:
Pomalidomide-C7-COOH

Biological Activity

[Description]:

Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

Cereblon[1]

[References]

[1]. Zhang X, et, al. Discovery of PROTAC BCL-X L degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15; 192: 112186.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₅N₃O₆

[ Molecular Weight ]:
415.44

[ Storage condition ]:
2-8°C

Related Compounds

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