Neuraminidase-IN-9

Names

[ Name ]:
Neuraminidase-IN-9

Biological Activity

[Description]:

Neuraminidase-IN-9 (Compound 6l) is a potent influenza neuraminidase inhibitor with IC50 values of 0.12, 0.049 and 0.16 µM against H5N1, H5N2 and H5N6, respectively[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

[Target]

IC50: 0.049 µM (H5N2), 0.12 µM (H5N1), 0.16 µM (H5N6)[1] EC50: 0.43 µM (H5N2), 2.45 µM (H5N1), 2.8 µM (H5N6)[1]

[References]

[1]. Ju H, et al. Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity. Eur J Med Chem. 2020 Feb 1;187:111940.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₃₃BrN₆O₃

[ Molecular Weight ]:
533.46

Related Compounds

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