DPP-4-IN-1

Names

[ CAS No. ]:
2215027-46-4

[ Name ]:
DPP-4-IN-1

Biological Activity

[Description]:

DPP-4-IN-1 (compound d1) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC50of 49 nM. DPP-4-IN-1 is a structurally analogs of Alogliptin (HY-A0023A). DPP-4-IN-1 can be used for diabetes research[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase
Research Areas >> Metabolic Disease

[Target]

DPP-IV:49 nM (IC50)


[References]

[1]. Shen J, et al. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112850.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H19ClN6

[ Molecular Weight ]:
366.85

Related Compounds