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Boc-Ala-Glu-Val-Asp-aldehyde (pseudo acid)

Names

[ CAS No. ]:
220094-15-5

[ Name ]:
Boc-Ala-Glu-Val-Asp-aldehyde (pseudo acid)

[Synonym ]:
boc-ala-glu-val-asp-aldehyde
boc-aevd-cho
boc-ala-glu-val-asp-cho

Biological Activity

[Description]:

Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Signaling Pathways >> Apoptosis >> Caspase
Research Areas >> Inflammation/Immunology

[Target]

Caspase 8[2].


[References]

[1]. Garcia-Calvo M, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13.  

[2]. Grassmé H, et al. Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene. 2003 Aug 21;22(35):5457-70.  

Chemical & Physical Properties

[ Density]:
1.258

[ Molecular Formula ]:
C22H36N4O10

[ Molecular Weight ]:
516.54

[ Exact Mass ]:
516.24300

[ PSA ]:
217.30000

[ LogP ]:
1.11200

Related Compounds