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GS-6207

Names

[ CAS No. ]:
2189684-44-2

[ Name ]:
GS-6207

Biological Activity

[Description]:

GS-6207 is a HIV-1 capsid inhibitor. GS-6207 shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. GS-6207 displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs)[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[References]

[1]. Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019 Jun 20;10:1227.

Chemical & Physical Properties

[ Molecular Formula ]:
C39H32ClF10N7O5S2

[ Molecular Weight ]:
968.28

Related Compounds