Eupatorin-5-methylether

Names

[ Name ]:
Eupatorin-5-methylether

[Synonym ]:
Eupatorin 5-Methyl Ether
3'-hydroxy-4',5,6,7-tetramethoxyflavone
2-(3,4dihydroxyphenyl)-5-hydroxy-7-[3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6 tetrahydropyran-2-yloxy)]chromen-4-one
5-OMe-eupatorin
3'-hydroxy-5,6,7,4'-tetramethoxyflavone

Biological Activity

[Description]:

Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Mirka Laavola, et al. Flavonoids Eupatorin and Sinensetin Present in Orthosiphon stamineus Leaves Inhibit Inflammatory Gene Expression and STAT1 Activation. Planta Med. 2012, 78, 08.

Chemical & Physical Properties

[ Density]:
1.309g/cm3

[ Boiling Point ]:
573.7ºC at 760mmHg

[ Melting Point ]:
179-180ºC

[ Molecular Formula ]:
C₁₉H₁₈O₇

[ Molecular Weight ]:
358.34200

[ Flash Point ]:
207.4ºC

[ Exact Mass ]:
358.10500

[ PSA ]:
87.36000

[ LogP ]:
3.20000

[ Vapour Pressure ]:
9.21E-14mmHg at 25°C

[ Index of Refraction ]:
1.593

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Related Compounds

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