trolamine salicylate

Names

[ Name ]:
trolamine salicylate

[Synonym ]:
Salicylic acid
triethanol-amine salicylate
Salicylic acid, compound with 2,2',2''-nitrilotriethanol (1:1)
trolamine salicylate
EINECS 218-531-3
2-Hydroxybenzoic acid - 2,2',2''-nitrilotriethanol (1:1)
Benzoic acid, 2-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:1)
2-Hydroxybenzoic acid, compd. with 2,2',2''-nitrilotris(ethanol) (1:1)
MFCD00082325
QVR BQ &Q2N2Q2Q
Q2N2Q2Q &QVR BQ
Triethanolamine salicylate
salicylic acid,compound with 2,2',2''-nitrilotriethanol (1:1)
TEA-Salicylate

Chemical & Physical Properties

[ Density]:
1.209 g/mL at 25 °C

[ Boiling Point ]:
335.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₂₁NO₆

[ Molecular Weight ]:
287.309

[ Flash Point ]:
113 °C

[ Exact Mass ]:
287.136902

[ PSA ]:
121.46000

[ Vapour Pressure ]:
8.38E-06mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.509

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S24/25-S36-S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Topical penetration of commercial salicylate esters and salts using human isolated skin and clinical microdialysis studies.

Br. J. Clin. Pharmacol. 46(1) , 29-35, (1998)

The penetration of active ingredients from topically applied anti-inflammatory pharmaceutical products into tissues below the skin is the basis of their therapeutic efficacy. There is still controvers...

Serum concentrations of salicylic acid following topically applied salicylate derivatives.

Ann. Pharmacother. 30(9) , 935-40, (1996)

To compare the rate and extent of systemic salicylate absorption following single and multiple applications of two topically applied analgesics, one containing methyl salicylate and the other containi...

Self promotion of deep tissue penetration and distribution of methylsalicylate after topical application.

Pharm. Res. 16(3) , 427-33, (1999)

To determine how changes in cutaneous blood flow induced in-vivo by methylsalicylate (MeSA), compared to non-rubefacient triethanolamine salicylate (TSA), affected topical salicylate absorption and di...