atrazine-2-hydroxy

Names

[ Name ]:
atrazine-2-hydroxy

[Synonym ]:
6-hydroxy-N2-ethyl-N4-(1-methylethyl)-1,3,5-triazine-2,4-diamine
4-Ethylamino-6-(Propan-2-Ylamino)-5H-1,3,5-Triazin-2-One
2-hydroxy-4-ethylamino-6-[1-methylethyl]-1,3,5-triazine-2,4-diamine
hydroxydechloroatrazine
N-ethyl-6-hydroxy-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine
6-hydroxy-N-2-ethyl-N-4-isopropyl-1,3,5-triazine-2,4-diamine
2-(ethylamino)-6-(propan-2-ylamino)-1H-1,3,5-triazin-4-one
4-(Ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine
2-Hydroxyatrazine
MFCD00078693
2-hydroxypropazine
Hydroxyatrazine
Hydroxy Atrazine
2-Hydroxy-4-ethylamino-6-isopropylamino-1,3,5-triazine
4-(ethylamino)-6-(isopropylamino)-s-triazin-2-ol
Atrazine-2-hydroxy

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
274.3ºC at 760mmHg

[ Molecular Formula ]:
C₈H₁₅N₅O

[ Molecular Weight ]:
197.23800

[ Flash Point ]:
119.7ºC

[ Exact Mass ]:
197.12800

[ PSA ]:
82.96000

[ LogP ]:
0.97530

[ Vapour Pressure ]:
0.00544mmHg at 25°C

[ Index of Refraction ]:
1.61

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ3018855

CHEMICAL NAME :: 1,3,5-Triazin-2(1H)-one, 4-(ethylamino)-6-((1-methylethyl)amino)-

CAS REGISTRY NUMBER :: 2163-68-0

LAST UPDATED :: 199606

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H15-N5-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7280 mg/kg/2Y-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - other changes

REFERENCE :: TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 23,771,1995

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
XZ3018855

[ HS Code ]:
2933699090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933699090

[ Summary ]:
2933699090 other compounds containing an unfused triazine ring (whether or not hydrogenated) in the structure。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:20.0%

Articles

Alteration of catecholamines in pheochromocytoma (PC12) cells in vitro by the metabolites of chlorotriazine herbicide.

Toxicol. Sci. 59(1) , 127-37, (2001)

The effects of four major chlorotriazine metabolites on the constitutive synthesis of the catecholamines dopamine (DA) and norepinephrine (NE) were examined, using undifferentiated PC12 cells. NE rele...

Pubertal development in female Wistar rats following exposure to propazine and atrazine biotransformation by-products, diamino-S-chlorotriazine and hydroxyatrazine.

Toxicol. Sci. 76(1) , 190-200, (2003)

We showed previously that the chlorotriazine herbicide, atrazine (ATR), delays the onset of pubertal development in female rats. ATR and its biotransformation by-products are present in soil and groun...

Soil leaching column chromatographic technique for estimation of leaching behavior of atrazine, deethylatrazine, deisopropylatrazine, and hydroxyatrazine on soil.

Bull. Environ. Contam. Toxicol. 63(1) , 87-93, (1999)