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RIPK2-IN-8

Names

[ CAS No. ]:
2141969-56-2

[ Name ]:
RIPK2-IN-8

Biological Activity

[Description]:

RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> RIP kinase
Research Areas >> Inflammation/Immunology

[Target]

IC50: 3 nM (RIPK2)[1]


[References]

[1]. He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H21FN4O3S

[ Molecular Weight ]:
392.45

Related Compounds