BRD-4592
Names
[ CAS No. ]:
2109805-80-1
[ Name ]:
BRD-4592
Biological Activity
[Description]:
A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo.
[References]
References 1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96. View Related Products by Target Bacterial
Chemical & Physical Properties
[ Molecular Formula ]:
C17H15FN2O
[ Molecular Weight ]:
282.318
Related Compounds
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