RN 9893 hydrochloride

Names

[ Name ]:
RN 9893 hydrochloride

Biological Activity

[Description]:

A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets.

[References]

References 1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. View Related Products by Target TRP Channel

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₃F₃N₄O₅S_.HCl

[ Molecular Weight ]:
536.95

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.