EML-633

Names

[ CAS No. ]:
2101954-85-0

[ Name ]:
EML-633

Biological Activity

[Description]:

A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity.

[References]

References 1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377. 2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₂H₆₂N₆O₂

[ Molecular Weight ]:
682.998

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.