EML-633
Names
[ CAS No. ]:
2101954-85-0
[ Name ]:
EML-633
Biological Activity
[Description]:
A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity.
[References]
References 1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377. 2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6. View Related Products by Target Other Targets
Chemical & Physical Properties
[ Molecular Formula ]:
C42H62N6O2
[ Molecular Weight ]:
682.998