TRV0109101 hydrochloride

Names

[ Name ]:
TRV0109101 hydrochloride

[Synonym ]:
6-Oxaspiro[4.5]decane-9-ethanamine, 9-(2-pyridinyl)-N-(2-thienylmethyl)-, (9R)-, hydrochloride (1:1)
2-[(9R)-9-(2-Pyridinyl)-6-oxaspiro[4.5]dec-9-yl]-N-(2-thienylmethyl)ethanamine hydrochloride (1:1)

Biological Activity

[Description]:

A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.

[References]

References 1. Koblish M, et al. J Pharmacol Exp Ther. 2017 Aug;362(2):254-262. View Related Products by Target Opioid Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₉ClN₂OS

[ Molecular Weight ]:
392.986

[ Exact Mass ]:
392.168915

Related Compounds

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