PROTAC RIPK degrader-6
Names
[ CAS No. ]:
2089205-64-9
[ Name ]:
PROTAC RIPK degrader-6
Biological Activity
[Description]:
PROTAC RIPK degrader-6 (example 1) is a PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder[1].
[Related Catalog]:
[Target]
Cereblon
[In Vitro]
PROTACs is useful for the targeted degradation of proteins and other polypeptides which on the one end binds to the cereblon and on the other end to the target protein (RIP2 kinase). By bringing the target protein in close proximity to the E3-Ligase, these compounds form a ternary complex leading to polyubiquitination of the target protein inducing its degradation[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C43H48N6O11S2
[ Molecular Weight ]:
889.00
[ Storage condition ]:
-20°C