HZ-A-005

Names

[ CAS No. ]:
2041789-14-2

[ Name ]:
HZ-A-005

Biological Activity

[Description]:

HZ-A-005 is a potent, selective, and covalent Bruton’s tyrosine kinase (BTK) inhibitor. HZ-A-005 markedly decreases tumor growth in xenograft mouse models[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[References]

[1]. Huang W, et al. HZ-A-005, a potent, selective, and covalent Bruton's tyrosine kinase inhibitor in preclinical development. Bioorg Chem. 2020;105:104377.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₃ClN₆O₂

[ Molecular Weight ]:
474.94

Related Compounds

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