3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI)

Names

[ CAS No. ]:
202979-51-9

[ Name ]:
3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI)

[Synonym ]:
5-epi-Isofagomine

Biological Activity

[Description]:

L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Pandey G, et al. A new access to polyhydroxy piperidines of the azasugar class: synthesis and glycosidase inhibition studies. Org Biomol Chem. 2003 Oct 7;1(19):3321-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₃NO₃

[ Molecular Weight ]:
147.17200

[ Exact Mass ]:
147.09000

[ PSA ]:
72.72000

Related Compounds

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