CPI-203

Names

[ CAS No. ]:
202591-23-9

[ Name ]:
CPI-203

[Synonym ]:
2-[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-2,3,9-trimethyl-, (6S)-
4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
CPI-203

Biological Activity

[Description]:

(Rac)-CPI-203 is a racemate of CPI-203 (HY-15846) (BET bromodomain inhibitor)[1]

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Moros A, et al. Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma. Leukemia. 2014 Oct;28(10):2049-59

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
690.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₈ClN₅OS

[ Molecular Weight ]:
399.897

[ Flash Point ]:
371.4±34.3 °C

[ Exact Mass ]:
399.092072

[ LogP ]:
1.85

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.749

[ Storage condition ]:
2-8℃

CPI-203

Names

Biological Activity

Chemical & Physical Properties

Related Compounds