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(S)-GNE-140

Names

[ CAS No. ]:
2003234-64-6

[ Name ]:
(S)-GNE-140

Biological Activity

[Description]:

(S)-GNE-140 is the less active enantiomer of GNE-140 which can inhibit Lactate dehydrogenase A (LDHA).

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase
Research Areas >> Cancer

[Target]

LDHA[1]


[References]

[1]. Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. ACS Med Chem Lett. 2016 Aug 26;7(10):896-901.


[Related Small Molecules]

GNE-140 racemate | GSK 2837808A | LDH-IN-1 | FX-11 | Nifurtimox

Chemical & Physical Properties

[ Molecular Formula ]:
C25H23ClN2O3S2

[ Molecular Weight ]:
499.04

Related Compounds