Chrysoeriol-7-O-glucoside

Names

[ CAS No. ]:
19993-32-9

[ Name ]:
Chrysoeriol-7-O-glucoside

[Synonym ]:
4H-1-Benzopyran-4-one, 7-(D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-
5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-7-yl D-glucopyranoside
Chrysoeriol 7-O-glucoside

Biological Activity

[Description]:

Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450

Research Areas >> Others

[References]

[1]. Omer I Fantoukh, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea ( Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019 May 1;67(17):4967-4975.

Chemical & Physical Properties

[ Density]:
1.609

[ Boiling Point ]:
801.6±65.0 °C at 760 mmHg

[ Melting Point ]:
176-179 ºC

[ Molecular Formula ]:
C₂₂H₂₂O₁₁

[ Molecular Weight ]:
462.404

[ Flash Point ]:
281.0±27.8 °C

[ Exact Mass ]:
462.116211

[ PSA ]:
179.28000

[ LogP ]:
-0.68

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.695

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream

Related Compounds

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