baloxavir marboxil

Names

[ CAS No. ]:
1985606-14-1

[ Name ]:
baloxavir marboxil

[Synonym ]:
baloxavir marboxil
10491
505CXM6OHG
({(12aR)-12-[(11S)-7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl}oxy)methyl methyl carbonate
Carbonic acid, [[(12aR)-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-3,4,6,8,12,12a-hexahydro-6,8-dioxo-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl]oxy]methyl methyl ester

Biological Activity

[Description]:

Baloxavir marboxil is a prodrug of S-033447. S-033447 is a small molecule inhibitor of the cap-dependent endonuclease of influenza A and B viruses.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Infection

[References]

[1]. Koszalka P, et al. Influenza antivirals currently in late-phase clinical trial. Influenza Other Respir Viruses. 2017 May;11(3):240-246.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
712.8±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₂₃F₂N₃O₇S

[ Molecular Weight ]:
571.549

[ Flash Point ]:
384.9±35.7 °C

[ Exact Mass ]:
571.122498

[ LogP ]:
2.24

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.696

[ Storage condition ]:
2-8℃

baloxavir marboxil

Names

Biological Activity

Chemical & Physical Properties

Related Compounds