MAK683
Names
Biological Activity
[Description]:
EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.
[Related Catalog]:
[Target]
IC50: 59 nM (EED Alphascreen), 89 nM (LC-MS), 26 nM (ELISA)[1]
[In Vitro]
EED inhibitor-1 has antiproliferative activities in B cell lymphoma cell KARPAS422 after 14 days of treatment with an IC50 of 30 nM[1].
[References]
[1]. US20160176882 A1
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666-15
Chemical & Physical Properties
[ Molecular Formula ]:
C20H17FN6O
[ Molecular Weight ]:
376.39
[ Storage condition ]:
2-8℃
Related Compounds
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