Piperazine,1,4-bis[bis(1-aziridinyl)phosphinothioyl]-
Names
[ CAS No. ]:
1950-08-9
[ Name ]:
Piperazine,1,4-bis[bis(1-aziridinyl)phosphinothioyl]-
[Synonym ]:
1,4-Bis(bis(1-aziridinyl)phosphinothioyl)piperazine
1,4-bis-(bis-aziridin-1-yl-phosphinothioyl)-piperazine
Thiodipin
Thiodipine
1,4-Bis-(diethylenimino-thiophosphono)-piperazin
Piperazine,1,4-bis(bis(1-aziridinyl)phosphinothioyl)
Phosphine sulfide,1,4-piperazinediylbis(bis(1-aziridinyl)
35P-Thiodipin
Chemical & Physical Properties
[ Molecular Formula ]:
C12H24N6P2S2
[ Molecular Weight ]:
378.43700
[ Exact Mass ]:
378.09800
[ PSA ]:
102.32000
[ LogP ]:
1.24400
[ Vapour Pressure ]:
7.04E-10mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TK8720000
- CHEMICAL NAME :
- Piperazine, 1,4-bis(bis(1-aziridinyl)phosphinothioyl)-
- CAS REGISTRY NUMBER :
- 1950-08-9
- BEILSTEIN REFERENCE NO. :
- 0629376
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C12-H24-N6-P2-S2
- MOLECULAR WEIGHT :
- 378.48
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg/10D-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thymus weight Related to Chronic Data - death
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,732,1961
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 gm/kg/10D-I
- TOXIC EFFECTS :
- Blood - leukopenia Related to Chronic Data - death
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,732,1961