1-Isomangostin

Names

[ CAS No. ]:
19275-44-6

[ Name ]:
1-Isomangostin

[Synonym ]:
5,9-dihydroxy-10-methoxy-2,2-dimethyl-11-(3-methylbut-2-enyl)-3,4-dihydropyrano[2,3-a]xanthen-12-one

Biological Activity

[Description]:

1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC50 of 34.5 μM. 1-Isomangostin has anti-obesity activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Chae, Hee-Sung, et al. Xanthones with pancreatic lipase inhibitory activity from the pericarps of Garcinia mangostana L. (Guttiferae). European Journal of Lipid Science and Technology, (), n/a–n/a.

Chemical & Physical Properties

[ Density]:
1.257g/cm3

[ Boiling Point ]:
613.9ºC at 760mmHg

[ Molecular Formula ]:
C₂₄H₂₆O₆

[ Molecular Weight ]:
410.46

[ Flash Point ]:
211.5ºC

[ Exact Mass ]:
410.17300

[ PSA ]:
89.13000

[ LogP ]:
4.97830

[ Vapour Pressure ]:
1.16E-15mmHg at 25°C

[ Index of Refraction ]:
1.604

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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