SuO-Glu-Val-Cit-PAB-MMAE

Names

[ Name ]:
SuO-Glu-Val-Cit-PAB-MMAE

Biological Activity

[Description]:

SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Auristatin

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₇H₁₀₃N₁₁O₁₇

[ Molecular Weight ]:
1334.60

SuO-Glu-Val-Cit-PAB-MMAE

Names

Biological Activity

Chemical & Physical Properties

Related Compounds