Cleroindicin F

Names

[ Name ]:
Cleroindicin F

[Synonym ]:
6(2H)-Benzofuranone, 3,3a,7,7a-tetrahydro-3a-hydroxy-, (3aR,7aR)-
4,7-Epoxy-1,3-benzodioxol-2-one,3a,4,7,7a-tetrahydro
rengyolone
(3aR,7aR)-3a-Hydroxy-3,3a,7,7a-tetrahydro-1-benzofuran-6(2H)-one
cleroindicin F

Biological Activity

[Description]:

Cleroindicin F ((-)-Rengyolone), a cleroindicin, is an antimicrobial agent. Cleroindicin F shows relatively high anticandidal activity against Candida strains with a MIC value down to 12.5 µg/mL[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Hasan Kirmizibekmez, et al. Secondary Metabolites from the Leaves of Digitalis viridiflora. Nat Prod Commun. 2017 Jan;12(1):59-61.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
332.9±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₁₀O₃

[ Molecular Weight ]:
154.16

[ Flash Point ]:
142.6±21.4 °C

[ Exact Mass ]:
154.062988

[ PSA ]:
46.53000

[ LogP ]:
-0.85

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.582

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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