(Asn⁶⁷⁰,Leu6⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-676) trifluoroacetate salt

Names

[ Name ]:
(Asn⁶⁷⁰,Leu6⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-676) trifluoroacetate salt

[Synonym ]:
(ASN670,LEU671)-APP770 (667-676)
H-Ser-Glu-Val-Asn
SEVNLDAEFR
A4 PROTEIN PRECURSOR770 (667-676)
SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG
H-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-OH
MFCD03097426
(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-676)

Biological Activity

[Description]:

SEVNLDAEFR is a substrate for BACE1[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Beta-secretase

Research Areas >> Neurological Disease

[Target]

BACE1[1]

[References]

[1]. Machálková M, et al. A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer's disease drug target β-secretase. Anal Bioanal Chem. 2018 Nov;410(28):7441-7448.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₅₀H₇₈N₁₄O₁₉

[ Molecular Weight ]:
1179.237

[ Exact Mass ]:
1178.556763

[ PSA ]:
562.34000

[ LogP ]:
-1.78

[ Appearance of Characters ]:
solid

[ Index of Refraction ]:
1.646

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.