(S)-Lercanidipine HCl

Names

[ Name ]:
(S)-Lercanidipine HCl

[Synonym ]:
1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1)
(4S)-1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
UNII-OA8TFX68PE component WMFYOYKPJLRMJI-WAQYZQTGSA-N
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester, (4S)-, hydrochloride (1:1)
(S)-Lercanidipine Hydrochloride

Biological Activity

[Description]:

(S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-lercanidipine hydrochloride is a potent calcium channel blocker[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Cardiovascular Disease

[References]

[1]. Wirtz S,et al. Molecular mechanisms of vasoselectivity of the 1,4-dihydropyridine lercanidipine. Br J Pharmacol. 2004 May;142(2):275-84.

Chemical & Physical Properties

[ Boiling Point ]:
712.5ºC at 760 mmHg

[ Melting Point ]:
116-122ºC

[ Molecular Formula ]:
C₃₆H₄₂ClN₃O₆

[ Molecular Weight ]:
648.188

[ Flash Point ]:
384.7ºC

[ Exact Mass ]:
647.276184

[ PSA ]:
113.69000

[ LogP ]:
8.13240

[ Vapour Pressure ]:
3.77E-20mmHg at 25°C

Related Compounds

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