leucomycin A6
Names
[ CAS No. ]:
18361-48-3
[ Name ]:
leucomycin A6
[Synonym ]:
Antibiotic yl-704 B3
Turimycin A3
Platenomycin-B3
Leucomycin V 3-acetate 4b-propanoate
Yl 704 B3
Leucomycin A6
Leukomycin A6
Chemical & Physical Properties
[ Density]:
1.22g/cm3
[ Boiling Point ]:
867ºC at 760mmHg
[ Molecular Formula ]:
C40H65NO15
[ Molecular Weight ]:
799.94200
[ Flash Point ]:
478.1ºC
[ Exact Mass ]:
799.43500
[ PSA ]:
206.05000
[ LogP ]:
2.37730
[ Vapour Pressure ]:
4.52E-35mmHg at 25°C
[ Index of Refraction ]:
1.537
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OH4725500
- CHEMICAL NAME :
- Leucomycin A6
- CAS REGISTRY NUMBER :
- 18361-48-3
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C40-H65-N-O15
- MOLECULAR WEIGHT :
- 800.06
- WISWESSER LINE NOTATION :
- T-16-OV KU MUTJ DOO2 EO1 G1VH I1 JQ P1 FO- BT6OTJ CQ DN1&1 F1 EO- FT6OTJ B1 COV2 DQ D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,810,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,87,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 4,193,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309